Postprandial Thermogenesis in Lean and Obese Subjects After Meals Supplemented with Medium-Chain Triglycerides (MCT)


Am J Clin Nutr. 1991 May;53(5):1130-3.

Postprandial thermogenesis in lean and obese subjects after meals supplemented with medium-chain and long-chain triglycerides.

Scalfi L1, Coltorti A, Contaldo F.
Institute of Internal Medicine and Metabolic Diseases, 2nd Medical School, University of Naples Federico II, Italy.

Abstract

BACKGROUND:
The thermic effect of medium-chain triglycerides (MCTs) was studied in six lean and six obese young males by evaluating postprandial thermogenesis (PPT) after the ingestion of mixed meals containing either 38 g long-chain triglycerides (LCTs) or 30 g MCTs plus 8 g LCTs. Postabsorptive resting metabolic rate (RMR) was higher (P less than 0.05) in the obese individuals than in the lean ones. PPT, evaluated as 6-h incremental areas above RMR, was greater (P less than 0.05) in both groups after meals containing MCTs. The thermic effect of MCTs was 119.7 +/- 33.9 and 144.7 +/- 48.8 kJ/6 h in the lean and the obese subjects, respectively. The postprandial response of glucose, insulin, and free fatty acids did not depend on the type of oil contained in the meal.

CONCLUSION:
Our study shows that PPT is enhanced in both lean and obese subjects when LCTs in a mixed meal are replaced with MCTs.

PMID: 2021124 [PubMed – indexed for MEDLINE]


Article published by the U.S. National Library of Medicine and the National Institute of Health, at http://www.ncbi.nlm.nih.gov/pubmed/2021124 and appeared there on April 13, 2014.

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